Detalhe da pesquisa
1.
Evaluating drug-drug interaction risk associated with peptide analogues using advanced in vitro systems.
Drug Metab Dispos
; 2023 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38050097
2.
Dicloxacillin-warfarin drug-drug interaction-A register-based study and in vitro investigations in 3D spheroid primary human hepatocytes.
Br J Clin Pharmacol
; 89(8): 2614-2624, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37021780
3.
A Novel Pathogenic UGT1A1 Variant in a Sudanese Child with Type 1 Crigler-Najjar Syndrome.
Drug Metab Dispos
; 47(1): 45-48, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30385458
4.
UGT1A10 Is a High Activity and Important Extrahepatic Enzyme: Why Has Its Role in Intestinal Glucuronidation Been Frequently Underestimated?
Mol Pharm
; 14(9): 2875-2883, 2017 09 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27966992
5.
Selectivity in the Efflux of Glucuronides by Human Transporters: MRP4 Is Highly Active toward 4-Methylumbelliferone and 1-Naphthol Glucuronides, while MRP3 Exhibits Stereoselective Propranolol Glucuronide Transport.
Mol Pharm
; 14(10): 3299-3311, 2017 10 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28850245
6.
Dog UDP-glucuronosyltransferase enzymes of subfamily 1A: cloning, expression, and activity.
Drug Metab Dispos
; 43(1): 107-18, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25301937
7.
Case report by Toce and co-authors: Have all the reasons for poor morphine glucuronidation been addressed?
Br J Clin Pharmacol
; 85(4): 859-860, 2019 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30737810
8.
Thermodynamic solubility measurement without chemical analysis.
Int J Pharm
; 653: 123890, 2024 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38346601
9.
3D Spheroid Primary Human Hepatocytes for Prediction of Cytochrome P450 and Drug Transporter Induction.
Clin Pharmacol Ther
; 113(6): 1284-1294, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36906857
10.
Flucloxacillin Is a Weak Inducer of CYP3A4 in Healthy Adults and 3D Spheroid of Primary Human Hepatocytes.
Clin Pharmacol Ther
; 114(2): 434-445, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37235733
11.
Clinical and Molecular Perspectives on Inflammation-Mediated Regulation of Drug Metabolism and Transport.
Clin Pharmacol Ther
; 112(2): 277-290, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34605009
12.
Tutorial: Statistical analysis and reporting of clinical pharmacokinetic studies.
Clin Transl Sci
; 15(8): 1856-1866, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35570335
13.
The Role of Uptake and Efflux Transporters in the Disposition of Glucuronide and Sulfate Conjugates.
Front Pharmacol
; 12: 802539, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35095509
14.
Human efflux transport of testosterone, epitestosterone and other androgen glucuronides.
J Steroid Biochem Mol Biol
; 197: 105518, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-31704245
15.
Efflux transport of nicotine, cotinine and trans-3'-hydroxycotinine glucuronides by human hepatic transporters.
Basic Clin Pharmacol Toxicol
; 125(6): 490-498, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31237077
16.
Efflux transport of estrogen glucuronides by human MRP2, MRP3, MRP4 and BCRP.
J Steroid Biochem Mol Biol
; 178: 99-107, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29175180
17.
Glucuronidation of estrone and 16α-hydroxyestrone by human UGT enzymes: The key roles of UGT1A10 and UGT2B7.
J Steroid Biochem Mol Biol
; 154: 104-11, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26220143